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Answer for the clue "A changer who lessens the purity or effectiveness of a substance ", 11 letters:
adulterator

Word definitions for adulterator in dictionaries

The Collaborative International Dictionary Word definitions in The Collaborative International Dictionary
Adulterator \A*dul"ter*a`tor\, n. [L.] One who adulterates or corrupts. [R.] --Cudworth.

WordNet Word definitions in WordNet
n. any substance that adulterates (lessens the purity or effectiveness of a substance); "it is necessary to remove the adulterants before use" [syn: adulterant ] a changer who lessens the purity or effectiveness of a substance

Wiktionary Word definitions in Wiktionary
n. One who or that which adulterates, or harms the purity of, something.

Usage examples of adulterator.

Evidence is procurable that they have been an artificially-reared people, feeding on the genius of inventors, transposers, adulterators, instead of the products of nature, for the last half century.