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Answer for the clue "Loosen (up) ", 5 letters:
limer

Word definitions for limer in dictionaries

Wikipedia Word definitions in Wikipedia
A limer , or lymer , was a kind of dog, a scenthound , used on a leash in Medieval times to find large game before it was hunted down by the pack. It was sometimes known as a lyam hound/dog or lime-hound , from the Middle English word lyam meaning 'leash'. ...

Wiktionary Word definitions in Wiktionary
Etymology 1 alt. (context obsolete English) A kind of dog kept on a lead; a bloodhound; a mongrel. n. (context obsolete English) A kind of dog kept on a lead; a bloodhound; a mongrel. Etymology 2 n. Someone who limes; someone who uses bird-lime or who limewashes. ...

The Collaborative International Dictionary Word definitions in The Collaborative International Dictionary
Limer \Lim"er\ (l[imac]m"[~e]r), n. A limehound; a limmer. --Chaucer.