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Answer for the clue "What 21- and 52-Across and 3- and 31-Down might be ", 6 letters:
spiked

Alternative clues for the word spiked

Word definitions for spiked in dictionaries

WordNet Word definitions in WordNet
adj. equipped with long sharp-pointed projections especially along the top of a wall or fence; "the fence was iron and spiked along the top" having a long sharp point having alcohol added; "a cup of brandy-laced coffee"; "he drank too much of the spiked ...

Wiktionary Word definitions in Wiktionary
1 (context of a beverage English) Containing alcohol or drugs, often without the informing those who partake. 2 Having spikes. 3 Of a graph or trend that has rapidly reached a maximum. v (en-past of: spike )

Usage examples of spiked.

Movements of precious metals and ambulatory currency spiked metropolitan areas, while consumer spending showed up as gangs of small people, one per million, flashing their spending areas and products like dust motes dancing on sunlight.

The animals were of the brindled variety, and each was garnished with a steel spiked collar.

One had on the most conservative two-piece suit I had ever seen, and the other was in a spiked leather bustier and stockings.

And she turned the lens to the west, toward the high, spiked tors of the Djenn Marre, toward the Great Rift and beyond, just to the north, Kunlung Mountain.

Her heart slithered up into her throat and she only recognized the apparition one thin moment before young Millward shoved the spiked head of his halberd into the intruders guts.

The twenty-four pounders, like the six field guns that should have been delivered to Baltimore, were likewise spiked, turned off their carriages, and jettisoned into the flooded ditch.

The gates were actually more like towers, with spiked chains that spanned the river.

She wandered the crooked streets for hours with her purse tucked under her arm and her mouth wide open, past bars, sidewalk cafes, tiny shops with handmade jewelry and secondhand clothing in the windows, spiry churches, private parks behind spiked wrought-iron gates, crooked old houses with high stoops, art galleries, little theaters.

Working briskly and cheerfully in her spiked hair and leotards, she encouraged the convict labor by passing out stim tabs from a pillbox on her wrist.

There were almost three hundred Termagants, eighty-five Striding Murderers, as many Long-horned Murderers, a hundred Blue Horrors, fifty-two squat, immensely powerful Fiends, their tails tipped with spiked steel balls, and eighteen Juggers.

Kierendal paused in the doorway long enough to be joined by her three overt guardsmassive ogres with unfiled tusks, wearing light chainmail painted with the scarlet and brass motif of the house and carrying wickedly spiked morningstars slung at their waists.

He was ankle-deep in marsh and the ground was already spiked with grass blades, bright green in the setting sun, when Don came hurtling in.

Shii studied her black decks and spiked hull and the flame cannons poking out from her gun deck.

Their helms were fitted with napeguards, cheekpieces and nasals, the high collars of their knee-length scaleshirts guarded most of the throat, and the plate greaves strapped to their lower legs included a kneecop which was spiked to facilitate climbing.

The helmet crested in a spiked ridge, and beneath it lay a crisscrossing spiderweb of thin bones.