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Answer for the clue "Causes increasing irritation ", 7 letters:
festers

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Word definitions for festers in dictionaries

Wiktionary Word definitions in Wiktionary
vb. (en-third-person singular of: fester )

Usage examples of festers.

Moreover, from Africa there is always something new in the way of tropical diseases, and presently Africa, if we let it continue to fester as it festers now, may produce an epidemic that will stand exportation to a temperate climate.