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Answer for the clue "Six: Prefix ", 4 letters:
hexa

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Wikipedia Word definitions in Wikipedia
Hexosaminidase A (alpha polypeptide) , also known as HEXA , is an enzyme that in humans is encoded by the HEXA gene , located on the 15th chromosome . Hexosaminidase A and the cofactor G activator protein catalyze the degradation of the G gangliosides and ...