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zalospirone

n. A piperazine antidepressant, abandoned because of its side effects.

Wikipedia
Zalospirone

Zalospirone (WY-47,846) is a selective 5-HT partial agonist of the azapirone chemical class. It was found to be effective in the treatment of anxiety and depression in clinical trials, but a high proportion of subjects dropped out due to side effects and development was subsequently never completed.