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The acronym XPG can refer to the following:

  • Paris Gare du Nord, railway station, IATA airport code.
  • X/Open Portability Guide, which specifies the requirements for any system which is intended to be a Unix system, and a predecessor to the POSIX standard
  • Xeroderma pigmentosum, complementation group G, a genetic disorder and a possible source of skin tumors
  • an endonuclease involved in nucleotide excision repair