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XMT can refer to:

  • Extensible MPEG-4 Textual Format, an XML-based file format for storing MPEG-4 data in a way suitable for further editing
  • Explicit multi-threading, a parallel computing paradigm designed around the Parallel Random Access Machine
  • Cray XMT - a multithreaded supercomputing architecture, the successor to the Cray MTA-2.
  • 8-hydroxyfuranocoumarin 8-O-methyltransferase, an enzyme