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XDS could refer to:

  • Extended Data Services, a US standard for TV metadata transmission
  • Direct Save Protocol (X Window Direct Save Protocol), an additional feature of the X Window System graphical user interface for Unix-like computer operating systems
  • Cross Enterprise Document Sharing, a system for sharing clinical documents between healthcare institutions
  • X-ray diffuse scattering, a materials analysis technique
  • Xerox Data Systems, the name for Scientific Data Systems after it was purchased by Xerox Corporation
  • Springfield Armory XDS, a variant of the Croatian-made HS2000 pistol designed for pocket carry