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WPXU

WPXU may refer to:

  • WPXU-TV, a television station (channel 35 analog/34 digital) licensed to serve Jacksonville, North Carolina, United States
  • WPXU-LD, a low-power television station (channel 38) licensed to serve Amityville, New York, United States, a translator for WPXN-TV
  • WBUI, a television station (channel 23 analog/22 digital) licensed to serve Decatur, Illinois, United States, which used the call sign WPXU from May 1998 to June 1999