WKSO can refer to:
- WKSO-TV, a television station (channel 29) licensed to Somerset, Kentucky, United States, a member of Kentucky Educational Television
- WKSO (FM), a radio station (97.3 FM) licensed to Natchez, Mississippi, United States
WKSO (branded as Kiss 97.3) is a radio station that serves the Natchez, Mississippi area with Hot AC music. The station is owned by First Natchez Radio Group. The station was originally Urban WNJJ-FM 97.3 JAMZ until flipping to Hot AC as KISS 97.3 with call letters WKSO-FM in 2003. In 2006, Kiss 97.3 has shifted to Adult Top 40.
This station plays retro hits of the 1990s and Today with a slight mix of the 1980s.
This station also has the same logo as WNKS KISS 95.1 in Charlotte, North Carolina a Top 40 Mainstream music station owned by CBS Radio.