WHOI may refer to:
- Woods Hole Oceanographic Institution, a research and graduate degree educational institute in Massachusetts
- WHOI (TV), a television station (channel 19 digital/19 virtual) licensed to Peoria, Illinois, United States
WHOI is the ABC- affiliated television station for North- Central Illinois that is licensed to Peoria. It broadcasts a high definition digital signal on UHF channel 19 from a transmitter on North Stewart Street in Creve Coeur, a village of Groveland Township. Owned by the Sinclair Broadcast Group, WHOI is operated through joint sales and shared services agreements by Quincy Media (owner of NBC affiliate WEEK-TV).
The two outlets share studios together on Springfield Road, along I-474, in East Peoria. Although it is sister to Fox affiliate WYZZ-TV (owned by Sinclair's partner company, Cunningham Broadcasting), that outlet is operated separately by the Nexstar Broadcasting Group at the facility of CBS outlet WMBD-TV.