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Wiktionary
what's up

phr. 1 (context idiomatic colloquial English) What are you doing?; what is happening? 2 (context informal English) how are you?; how are you feeling? 3 (context idiomatic colloquial English) what's the matter? 4 (context rhetorical question colloquial English) A casual greeting with a meaning similar to ''how are you''? or ''nice to meet you''.

Wikipedia
What's up (phrase)

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What's up

What's up may refer to:

  • What's Up? (musical), a Lerner and Loewe musical
  • "What's Up?" (song), a song by 4 Non Blondes
  • What's Up!, a Swedish boyband
  • What'z Up?, a 1994 TV show
What's Up (TV series)

What's Up is a 2011 South Korean television series starring Lim Ju-hwan, Daesung, Lim Ju-eun, Oh Man-seok, Jang Hee-jin, Lee Soo-hyuk, Kim Ji-won and Jo Jung-suk. It aired on MBN on Saturdays to Sundays at 23:00 for 20 episodes beginning December 3, 2011.