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The Collaborative International Dictionary
Wanion

Wanion \Wan"ion\, n. [Probably for OE. waniand waning, p. pr. of wanien; hence, used of the waning of the moon, supposed to be an unlucky time. See Wane.] A word of uncertain signification, used only in the phrase with a wanion, apparently equivalent to with a vengeance, with a plague, or with misfortune. [Obs.]
--B. Jonson. Latimer.

Wiktionary
wanion

n. 1 the wane of the moon 2 curse 3 (context obsolete English) vengeance