What is "vchsr"

VCHSR is a drug used in scientific research which acts as a selective antagonist of the cannabinoid receptor CB. It is derived from the widely used CB antagonist rimonabant, and has similar potency and selectivity for the CB receptor, but has been modified to remove the hydrogen bonding capability in the C-3 substituent region, which removes the inverse agonist effect that rimonabant produces at high doses, so that VCHSR instead acts as a neutral antagonist, blocking the receptor but producing no physiological effect of its own.