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Usme is the 5th locality of the Capital District of Bogotá, capital city of Colombia. Usme is located in the southwestern part of Bogotá bordering to the north the localities of San Cristóbal, Rafael Uribe Uribe and Tunjuelito, to the west the locality of Ciudad Bolívar, to the south the locality of Sumapaz, and to the east the municipalities of Ubaque, Chipaque and Une in the Department of Cundinamarca.

Usme's urban area is separated from the main urban area of Bogotá, but the locality includes neighborhoods of south Bogotá.