Ushio may refer to:
- Japanese destroyer Ushio, a World War II IJN ship,
- Keizo Ushio, a Japanese sculptor
- Ushio Okazaki, a fictional character from Clannad (visual novel).
- Ushio (magazine) (潮), a Japanese magazine which has a strong connection with Soka Gakkai.
- Ushio Shuppansha (潮出版社）, the Japanese publisher.
- Ushio Inc., partner of Jenoptik AG in an Intel funding for an EUV-Lithography joint-venture.
- Ushio and Tora, a Japanese manga.