UPT and Upt can stand for:
- United Protective Technologies
- Universal Personal Telecommunications
- Unlimited Paenga Tawhiti - Designated special character secondary school in Christchurch City, New Zealand
- Upton railway station in the UK
- United Paramount Theaters
- An entry on the extended periodic table
- Unknown Primary Tumour - When a subject has metastatic disease but the primary tumour has not been identified
- Universitatea "Politehnica" din Timişoara ( Polytechnic University of Timișoara), Romania
- Acronym for United States Air Force's Undergraduate Pilot Training, officially JSUPT (Joint Specialized Undergraduate Pilot Training)
- University of Pittsburgh at Titusville
- Uptown New Orleans
- Units Per Transaction
- Urine pregnancy test
- Acronym for Unattended Payment Terminal, a formal name for ticket machines at parking lots (e.g. pay and display systems) and similar sites.
- Unpenttrium - a hypothetical chemical element in the periodic table with the temporary symbol Upt.