Wiktionary
a. (context idiomatic English) operational, in operation
Usage examples of "up and running".
Slipped them some material on deconstructionism and they were up and running.
Even before the dust had begun to settle they were up and running, masks and filters enabling them to breathe where others could not while simultaneously disguising their identities.
General Diggs had a second terminal up and running, and Tucker just stole its take.
A CADset was up and running, Natalie Dreyer was on one of her interminable excursions to the university libraries, and someone—.
When we reached the Destiny, they had the most vital systems up and running, but the interface between engineering and the drives had been destroyed.
The local station director says that the ansibles here are up and running, but we aren’.
Started with an empty field, designed the buildings and had the school up and running within two months.