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The Collaborative International Dictionary
Unsoul

Unsoul \Un*soul"\, v. t. [1st pref. un- + soul.] To deprive of soul, spirit, or principle. [R.]
--Shelton.

Wiktionary
unsoul

vb. To deprive of soul, spirit, or principle.

Usage examples of "unsoul".

A naughty view of a souled creature is much more effective than of an unsouled one.

So there might be an intelligent unsouled animal, like a dragon, hiding here in the Region of Madness.