Wiktionary
two-seam fastball
n. (context baseball English) A pitch thrown with a grip in the "horseshoe" orientation of the ball, with the rotation at a slight angle resulting in less http://en.wikipedia.org/wiki/Magnus%20effect as compared to a four-seam fastball since only two of the ball's seams cross the flight path; the pitch is delivered with a similar velocity as a four-seam fastball, but has a degree of sink.
Wikipedia
Usage examples of "two-seam fastball".
He manipulated the baseball with his right hand--index and middle fingers on top, thumb below--holding it with differ- ent grips four-seam fastball, two-seam fastball, curveball.