Most commonly, TUCC stands for:
- The Urology Center of Colorado
- Trinity United Church of Christ, an African-American megachurch in Chicago, whose most notable congregant was Barack Obama before he repudiated his membership.
It can also stand for:
- Tasmania University Cricket Club, also known as the "Lions"
- Trade Union Coordination Committee
- Transport Users' Consultative Committee
- Triangle Universities Computation Center, based in Research Triangle Park, NC