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6-Methoxy-(8-p-toluenesulfonamido)quinoline (TSQ) is one of the most efficient fluorescent stains for zinc(II). It was introduced by Soviet biochemists Toroptsev and Eshchenko in the early 1970s. The popularity of TSQ as physiological stain rose after seminal works by Christopher Frederickson two decades later. TSQ forms a 2:1 (ligand-metal) complex with zinc and emits blue light upon excitation at 365 nanometers. TSQ has been extensively applied for determination of extracellular or intracellular levels of Zn in biological systems, also to study Zn in mossy fibers of the hippocampus.

TSQ (disambiguation)

TSQ is 6-Methoxy-(8-p-toluenesulfonamido)quinoline, one of the most efficient fluorescent stains for zinc(II).

TSQ may also refer to:

  • Tianshengqiao-I Dam, an embankment dam and hydroelectric power station on the Nanpan River in China
  • tsq, ISO 639-3 code for Thai Sign Language
  • Toronto String Quartette, any of various string quartettes in Toronto, Canada
  • Transgender Studies Quarterly, the first non-medical academic journal devoted to transgender studies
  • Trauma Screening Questionnaire, a questionnaire that pre-assesses posttraumatic stress disorder