Touffe may refer to:
- Touffe, French for Tuft (disambiguation)
- Touffe, French slang for a female mons pubis
- Le Touffe, a character played by Pierre-François Martin-Laval in the 2004 film RRRrrrr!!!
- La touffe de sauge, a play by Laurent Tailhade
- Le Fils Touffe, play that served as inspiration for The Bing Boys Are Here