Topľa is a river in eastern Slovakia and right tributary of the Ondava. It is 129.8 km long and its basin covers an area of . It rises in the Čergov mountains, flows through Ondava Highlands, Beskidian Piedmont, Eastern Slovak Hills and Eastern Slovak Flat and flows into the Ondava in the cadastral area of Parchovany. It flows through the towns of Bardejov, Giraltovce, Hanušovce nad Topľou and Vranov nad Topľou.
Topla is a village in the municipality of Bor, Serbia. According to the 2002 census, the village has a population of 100 people.