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The Collaborative International Dictionary
To lose one's mind

Mind \Mind\ (m[imac]nd), n. [AS. mynd, gemynd; akin to OHG. minna memory, love, G. minne love, Dan. minde mind, memory, remembrance, consent, vote, Sw. minne memory, Icel. minni, Goth. gamunds, L. mens, mentis, mind, Gr. me`nos, Skr. manas mind, man to think. [root]104, 278. Cf. Comment, Man, Mean, v., 3d Mental, Mignonette, Minion, Mnemonic, Money.]

  1. The intellectual or rational faculty in man; the understanding; the intellect; the power that conceives, judges, or reasons; also, the entire spiritual nature; the soul; -- often in distinction from the body.

    By the mind of man we understand that in him which thinks, remembers, reasons, wills.
    --Reid.

    What we mean by mind is simply that which perceives, thinks, feels, wills, and desires.
    --Sir W. Hamilton.

    Let every man be fully persuaded in his own mind.
    --Rom. xiv. 5.

    The mind shall banquet, though the body pine.
    --Shak.

  2. The state, at any given time, of the faculties of thinking, willing, choosing, and the like; psychical activity or state; as:

    1. Opinion; judgment; belief.

      A fool uttereth all his mind.
      --Prov. xxix. 11.

      Being so hard to me that brought your mind, I fear she'll prove as hard to you in telling her mind.
      --Shak.

    2. Choice; inclination; liking; intent; will.

      If it be your minds, then let none go forth.
      --2 Kings ix. 15.

    3. Courage; spirit.
      --Chapman.

  3. Memory; remembrance; recollection; as, to have or keep in mind, to call to mind, to put in mind, etc.

    To have a mind or To have a great mind, to be inclined or strongly inclined in purpose; -- used with an infinitive. ``Sir Roger de Coverly . . . told me that he had a great mind to see the new tragedy with me.''
    --Addison.

    To lose one's mind, to become insane, or imbecile.

    To make up one's mind, to come to an opinion or decision; to determine.

    To put in mind, to remind. ``Regard us simply as putting you in mind of what you already know to be good policy.''
    --Jowett (Thucyd. ).

Usage examples of "to lose one's mind".

Standing with Ben on Cardassia, he'd seen how easy it could be to lose one's mind from horror.