TMB may refer to:
- Tamilnad Mercantile Bank Limited, a private sector bank in India
- Texas Medical Board
- Kendall-Tamiami Executive Airport near Miami in Florida, United States ( IATA airport codeTMB)
- Tour du Mont Blanc, a long distance walk around Mont Blanc
- 3,3’,5,5’-Tetramethylbenzidine, a chemical compound that is used in immunohistochemistry.
- The University of Southern California Trojan Marching Band, better known as the Spirit of Troy
- Transports Metropolitans de Barcelona, the main public transportation operator in Barcelona, Spain.
- Tri-Modular Block, a term from music theory related to a special kind of Sonata form exposition.
- Thai Military Bank, a retail bank in Thailand
- Tensions Mountain Boys
- To My Boy
- Tomorrow's Modern Boxes, an album by Thom Yorke
- Touch My Body
- The Mighty Boosh
- The Mighty B!
- The Moody Blues
- Technical Management Board, a Technical Committee of ISO
- The Midnight Beast, a British comedy music group
- Temagami metavolcanic belt, a geologic feature in Temagami, Ontario, Canada