Wikipedia
Thienotriazolodiazepine
A thienotriazolodiazepine is a heterocyclic compound containing a diazepine ring fused to a thiophene and triazole rings. Thienotriazolodiazepine forms the central core of several pharmaceutical drugs including:
- Brotizolam
- Ciclotizolam
- Deschloroetizolam
- Etizolam
- Metizolam
Thienotriazolodiazepines interact with the benzodiazepine receptor site, they typically have similar effects as 1,4- benzodiazepines (such as diazepam) and triazolobenzodiazepines (such as alprazolam).
Thienotriazolodiazepines that are not GABA receptor positive allosteric modulators include:
- Israpafant
- JQ1