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TFC may refer to:

  • Tastee Fried Chicken, a Nigerian fast-food chain
  • Tohokushinsha Film Corporation, a film distributor and production company based in Akasaka, Minato, Tokyo
  • Terrace F. Club, an eating club at Princeton university
  • Tanglewood Festival Chorus, the Boston Symphony's chorus since 1970
  • Team Fortress Classic, a first-person shooter video game
  • Teenage Fanclub
  • Tennessee Farmers Cooperative, an agricultural cooperative in Tennessee
  • The Final Cartridge III, a cartridge to freeze and save on Commodore 64 computer
  • The Final Cut (disambiguation)
  • Telford Central railway station, Shropshire, England National Rail code
  • Thin film composite membrane
  • The Fat Controller, the controller of the North Western Railway from the Thomas the Tank Engine and Friends franchise
  • Turner Fenton Campus, a high school in Brampton, Ontario, Canada (now renamed to Turner Fenton Secondary School)
  • The Fight Club, a Canadian promotion out of Edmonton, Alberta
  • The Filipino Channel, is an international Filipino broadcasting service owned by ABS-CBN
  • Triangular fibrocartilage, an articular discus found in the wrist