TDC may refer to:
- Hong Kong Trade Development Council
- TDC A/S, the largest Danish telecommunications company
- TDC, the U.S. ticker symbol for Teradata Corporation
- Time-to-digital converter, a device in signal processing
- Top dead center, the position farthest from the crankshaft of a piston in a reciprocating engine
- Torpedo Data Computer, a piece of naval technology
- Total delivery cost
- Trophée des champions
- Tristan da Cunha
- Theta Delta Chi
- Tokyo Dome City
- Texas Department of Criminal Justice, formerly the Texas Department of Corrections
- Trainee Detective Constable, the most junior British police Criminal Investigation Department (CID) rank, see Police ranks of the United Kingdom.
- Type Directors Club
- The Death Cure, book 3 in The Maze Runner series.