Wiktionary
take a run at
vb. 1 (context transitive idiomatic English) To attempt to achieve or acquire. 2 (context transitive idiomatic English) To attack or challenge or to try to attack or challenge.
Usage examples of "take a run at".
The Haladina, having learned to cut with a knife before they cut their teeth, decided to take a run at my people anyway, to see what they would see.
But we should take a run at their files and see what we can find,".
Within less than ten minutes the block had burned down enough for them to take a run at it, but they waited until there were no signs of live embers to continue on.
Random was not a good person to take a run at on a dark night when she was feeling a little strung out.