TACC may refer to:
- The 618th Air and Space Operations Center (Tanker Airlift Control Center), 618th AOC (TACC), a United States Air Force unit
- Texas Advanced Computing Center, a research center at the University of Texas at Austin
- Teens Against Cyber Crime, a cyber watch dog organization working with law enforcement to apprehend online criminals.
- Territorial Approach to Climate Change, a programme undertaken by the United Nations.
- Territorial Army Commissioning Course, a three-week course run at the Royal Military Academy Sandhurst for officer cadets commissioning into the UK Army Reserve (formerly the Territorial Army).
- Turkish American Community Center, a non-profit organization in the Washington metropolitan area.