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SXT may refer to:

  • Soft X-ray transient or X-ray nova
  • soft X-ray telescope, a telescope that views soft X-rays
    • an instrument on the Yohkoh (SOLAR-A) space probe
    • an instrument on the Astrosat space probe
    • an instrument on the Hitomi (ASTRO-H) space probe
  • Saxitoxin
  • Co-trimoxazole
  • SXT Technology Solutions, a European telecommunications company
  • the ICAO airline code for Servicios De Taxi Aéreo, see Airline codes-S
  • the rail code for the Salem Town railway station, see List of railway stations in India
  • the NYSE stock ticker symbol for Sensient Technologies Corporation
  • the sign extend operation for the PDP-11 architecture
  • SXT the former trim model for a Dodge Grand Caravan.