Crossword clues for streptokinase
Wiktionary
n. (context enzyme English) Any of a class of enzymes that catalyzes the conversion of plasminogen to plasmin and are used to dissolve blood clots
WordNet
n. an enzyme produced by some strains of streptococcus that can liquefy blood clots by converting plasminogen to plasmin; used medicinally in some cases of myocardial infarction and pulmonary embolism
Wikipedia
Streptokinase (SK) is an enzyme secreted by several species of streptococci that can bind and activate human plasminogen. SK is used as an effective and inexpensive thrombolysis medication in some cases of myocardial infarction (heart attack) and pulmonary embolism.
Streptokinase belongs to a group of medications known as fibrinolytics, and complexes of streptokinase with human plasminogen can hydrolytically activate other unbound plasminogen by activating through bond cleavage to produce plasmin. There are three domains to streptokinase, denoted α (residues 1–150), β (residues 151–287), and γ (residues 288–414). Each domain binds plasminogen, although none can activate plasminogen independently.
It is on the World Health Organization's List of Essential Medicines, the most important medications needed in a basic health system. The wholesale cost is between 30.00 and 138.00 USD per dose as of 2014. It is no longer available in the United States.
Usage examples of "streptokinase".
And it could do it many different ways: strep produced an enzyme, streptokinase, that dissolved coagulated plasma.
A single microscopic bacterium, too small to see with the naked eye, but containing the genes for a heart-attack enzyme, streptokinase, or for "ice-minus," which prevented frost damage to crops, might be worth five billion dollars to the right buyer.