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SSFL may refer to:

  • Santa Susana Field Laboratory, a nuclear and aerospace research facility in Simi Valley, California
  • Southern States Football League, a semi-pro American football league based in Florida
  • Southern Sydney Freight Line, a railway line under construction in Sydney, Australia
  • South of Scotland Football League, an amateur soccer league in Scotland
  • Staffordshire Senior Football League, a defunct English football league
  • Super Sunday Football League, a semi-pro / amateur soccer league in South Korea