Wikipedia
Simmondsin
Simmondsin is an extract of jojoba seeds (pronounced "ho-HO-bah") ( Simmondsia chinensis), it was traditionally thought to be a toxic substance due to jojoba seed meal causing weight loss in animals, but in year 2000 been researched as a potential treatment for reducing appetite of obese individuals by helping to reduce craving for food. Several mechanisms of action are thought to be involved in the appetite suppressant effect.