is an area in Minato, Tokyo, Japan, located adjacent to Shinbashi and Ginza, near Tokyo Bay and the Hamarikyu Gardens. Formerly a railway terminal, Shiodome has been transformed into one of Tokyo's most modern areas. It is a collection of 11 tiny town districts or cooperative zones, but generally there are three main areas:
- The , a collection of skyscrapers containing mostly businesses, hotels, and restaurants. Its thirteen skyscrapers house the headquarters of All Nippon Airways, Dentsu, Fujitsu, JSR, Mitsui Chemicals, Nippon Express, Nippon Television, Sega Sammy Holdings and Softbank.
- The western district, located west of the JR tracks and populated by European-style buildings.
- The southern extension, east of the JR tracks from Hamamatsucho 1-chome. This area is for residential use, and there are three tall apartment buildings located there, along with a small park.
Shiodome Station is a stop on the Yurikamome and Toei Ōedo Line; the complex is also within walking distance of Shimbashi Station.