SCSC is an acronym which may refer to:
- The Superconducting Super Collider, a canceled particle accelerator
- The Standing Council of Scottish Chiefs, an organization composed of the chiefs of many Scottish clans
- Sheffield City Swimming Club, a swimming club based in Sheffield
- The Society of Caddy Spoon Collectors, a UK-based membership organisation with world-wide membership
- Santa Clara Swim Club, a youth swim team in Santa Clara, CA.