Wiktionary
screw over
vb. (context transitive slang English) To cheat someone, or ruin their chances in a game or other situation.
Usage examples of "screw over".
We can't ask him to screw over his own board, but he knows what flag to salute, Jack.
He could take a round piece of ordinary, rolled steel, drill it out and tap it so it would screw over the barrel, making a solid plug.
Rich people will screw over poor ones till the world drowns in its own filth.