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Sanaria

Sanaria is a biotechnology company dedicated to the production of whole parasite vaccines protective against malaria, as well as related products for use in malaria research. Sanaria’s vaccines are based on the use of the sporozoite stage of the Plasmodium parasite as immunogen, an approach to immunization that has already proven highly protective in humans when delivered by the bite of mosquitoes. Sanaria has developed the technology to grow and harvest large quantities of aseptic, purified Plasmodium sporozoites and formulate them for use in vaccines for human use. Sanaria's initial candidate vaccine is called Sanaria PfSPZ, and uses radiation attenuated Plasmodium falciparum sporozoites as immunogen. Sanaria is developing other vaccines, including SanariaCVac , which uses unattenuated sporozoites in the presence of antimalarial drugs as immunogen; genetically attenuated sporozoites as immunogen, and other species of Plasmodium in al these formulations.