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salinosporamide

n. A highly cytotoxic proteasome inhibitor obtained from a marine bacterium

Wikipedia
Salinosporamide

The salinosporamides are a group of closely related chemical compounds isolated from marine bacteria in the genus Salinispora. They possess a densely functionalized γ-lactam-β-lactone bicyclic core.

Salinosporamide A has attracted interest for its potential use in treating various types of cancer.

In addition, a variety of synthetic analogs have been prepared.