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RWJ may refer to:

  • Ray William Johnson (born 1981), American actor and comedian
  • Robert Wood Johnson, the name shared by members of the family that descended from the president of Johnson & Johnson
    • Robert Wood Johnson I (1845–1910), American entrepreneur and industrialist and one of the three founding brothers of Johnson & Johnson
    • Robert Wood Johnson II (1893–1968), American businessman
    • Robert Wood Johnson III (1920–1970), American philanthropist and businessman
    • Woody Johnson (Robert Wood Johnson IV, born 1947), American businessman and philanthropist
    • Robert Wood Johnson Foundation, the United States' largest philanthropy devoted exclusively to health and health care
    • Robert Wood Johnson Medical School, a medical school whose stated purpose is education, research, health care delivery, and the promotion of community health
    • Robert Wood Johnson University Hospital, central New Jersey's Only Level 1 Trauma and academic medical center
  • Robert Ward Johnson, Democratic United States Senator and Confederate States Senator from the state of Arkansas
  • RWJ Airpark, a public-use airport located in Beach City, Chambers County, Texas, United States
  • RWJ-394674, a potent, orally active analgesic drug, which produces little respiratory depression
  • RWJ-51204, is an anxiolytic drug used in scientific research.