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RPR may refer to:

In science:

  • RPR problem diagnosis, a method designed to determine the root cause of IT problems
  • RPRD2 gene, which encodes the KIAA0460 protein
  • RprA RNA, a gene that encodes a 106 nucleotide regulatory non-coding RNA
  • Flopristin, also known as "RPR 132552A", a semi-synthetic antibiotic of the streptogramin A class
  • Rapid plasma reagin, a modern screening test for antibodies in the serum of patients with syphilis

In politics:

  • Rally for the Republic, or Rassemblement pour la République, a defunct French political party
  • Republican Party of Russia – People's Freedom Party, or RPR-PARNAS, a Russian liberal democratic political party
  • Romanian People's Republic or Republica Populară Romînă, the name of Communist Romania from 1947 to 1965

In transportation:

  • Richmond Pacific Railroad, a California terminal railroad owned by the Levin-Richmond Terminal Corporation
  • Swami Vivekananda Airport, the IATA code for the airport in India
  • Redlands Passenger Rail

In other:

  • Registered Professional Reporter, a certification provided by the National Court Reporters Association
  • Resilient Packet Ring (also known as IEEE 802.17), a standard designed for the optimized transport of data traffic over fiber rings