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RLU may refer to:

  • Relative light unit, a unit for measuring cleanliness by measuring the levels of Adenosine Triphosphate
  • Remote line unit, a type of switch in the GTD-5 EAX switching system
  • RLU-1 Breezy, an American homebuilt aircraft design
  • Rusline, a Russian airline whose IACO airline code is RLU