What is "restless legs syndrome"

alt. A neurological disorder characterized by an irresistible urge to move one's body to stop uncomfortable or odd sensations, usually in the legs. n. A neurological disorder characterized by an irresistible urge to move one's body to stop uncomfortable or odd sensations, usually in the legs.

n. feeling of uneasiness and restlessness in the legs after going to bed (sometimes causing insomnia); may be relieved temporarily by walking or moving the legs [syn: restless legs, Ekbom syndrome]

Restless legs syndrome (RLS) is a disorder that causes a strong urge to move one's legs. There is often an unpleasant feeling in the legs that improves somewhat with moving them. Occasionally the arms may also be affected. The feelings generally happen when at rest and therefore can make it hard to sleep. Due to the disturbance in sleep people may have daytime sleepiness, low energy, irritability, and a depressed mood. Additionally, many have limb twitching during sleep.

Risk factors for RLS include low iron levels, kidney failure, Parkinson disease, diabetes, rheumatoid arthritis, and pregnancy. A number of medications may also trigger the disorder including antidepressants, antipsychotics, antihistamines, and calcium channel blockers. There are two main types: one that starts early in life and another which starts later in life. The one that starts early tends to run in families and gets worse over time. The one that starts later tends to start suddenly but not get worse. Diagnosis is generally based on a person's symptoms after ruling out other potential causes.

Restless leg syndrome may resolve if the underlying problem is dealt with. Otherwise treatment includes lifestyle changes and medication. Lifestyle changes that may help including stopping alcohol and tobacco and sleep hygiene. Medications used include levodopa or a dopamine agonist such as pramipexole. RLS affects an estimated 2.5–15% of the American population. Females are more commonly affected than males and it becomes more common with age.