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Reolysin

Reolysin® (pelareorep; Wild-Type Reovirus; Serotype 3 Dearing; Oncolytics Biotech), is a proprietary formulation of the human reovirus ( reovirus) being developed for the treatment of various cancers and cell proliferative disorders. Reolysin is classified as an oncolytic virus, a virus that preferentially lyses cancer cells. Clinical trials have demonstrated that Reolysin may have activity across a variety of cancer types when administered alone and in combination with other cancer therapies.

In April 2015 the US FDA granted Orphan Drug Designation to Reolysin for malignant glioma.