What is "renanolone"

Renanolone ( INN), or 11-ketopregnanolone, is a semisynthetic neuroactive steroid which was described as a general anesthetic, but was never introduced for clinical use. Its isomers, alfaxolone and alfadolone, are also general anesthetics, and are known to act as positive allosteric modulators of the GABA receptor, a property which is almost certain to be the case for renanolone as well.