What is "pyoverdine"

n. (context biochemistry English) A fluorescent siderophore produced by the bacterium ''Pseudomonas aeruginosa''

Pyoverdine (or pyoverdin) are fluorescent siderophores produced by certain pseudomonad bacteria species.

In Pseudomonas aeruginosa PAO1 there are 14 pvd genes involved in the biosynthesis of pyoverdine.

Unlike Enterobactin, Pyoverdine/pseudobactins are iron-binding non-ribosomal peptides containing a dihydroxyquinoline derivative. The structure of the peptide differs between pseudomonads and over 40 structures have been described, while the chromophore, (1S)-5-amino-2,3-dihydro- 8,9-dihydroxy-1H-pyrimido[1,2-a]quinoline-1-carboxylic acid, is the same with the exception of azobactin from Azotobacter vinelandii, which possesses an extra urea ring.

Structure of the peptide backbone in various fluorescent Pseudomonas strains. Amino acid three-letter code are used along with Q=chromophore, DXxx= D amino acid, aThr=allo-threonine, c=cyclic structure, cOHOrn=cyclo-hydroxyornithine, Dab=diaminobutyric acid, Ac=Acetyl, Fo=formyl OH=hydroxyl

Pseudomonad species

Strain

Structure of the pyoverdine peptide chain

P. aeruginosa

ATCC15692

Q-DSer-Arg-DSer-FoOHOrn-c(Lys-FoOHOrn-Thr-Thr)

P. aeruginosa

ATCC27853

Q-DSer-FoOHDOrn-Orn-Gly-aDThr-Ser-cOHOrn

P. aeruginosa

Pa6

Q-DSer-Dab-FoOHOrn-Gln-DGln-FoOHDOrn-Gly

P. chlororaphis

ATCC9446

Q-DSer-Lys-Gly-FoOHOrn-c(Lys-FoOHDOrn-Ser)

P. fluorescens bv.I

ATCC13525

Q-DSer-Lys-Gly-FoOHOrn-c(Lys-FoOHDOrn-Ser)

P. fluorescens bv.I

9AW

Q-DSer-Lys-OHHis-aDThr-Ser-cOHOrn

P. fluorescens bv.III

ATCC17400

Q-DAla-DLys-Gly-Gly-OHAsp-DGln/Dab-Ser-DAla-cOHOrn

P. fluorescens bv.V

51W

Q-DAla-DLys-Gly-Gly-OHDAsp-DGln-DSer-Ala-Gly-aDThr-cOHOrn

P. fluorescens bv.V

1W

Q-DSer-Lys-Gly-FoOHOrn-c(Lys-FoOHDOrn-Ser)

P. fluorescens bv.V

10CW

Q-DSer-Lys-Gly-FoOHOrn-c(Lys-FoOHDOrn-Ser)

P. fluorescens bv.VI

PL7

Q-DSer-AcOHDOrn-Ala-Gly-aDThr-Ala-cOHOrn

P. fluorescens bv.VI

PL8

Q-DLys-AcOHDOrn-Ala-Gly-aDThr-Ser-cOHOrn

P. fluorescens

1.3

Q-DAla-DLys-Gly-Gly-OHAsp-DGln/Dab-Gly-Ser-cOHOrn

P. fluorescens

18.1

Q-DSer-Lys-Gly-FoOHOrn-Ser-DSer-Gly-c(Lys-FoOHDOrn-Ser)

P. fluorescens

CCM 2798

Q-Ser-Dab-Gly-Ser-OHDAsp-Ala-Gly-DAla-Gly-cOHOrn

P. fluorescens

CFBP 2392

Q-DLys-AcOHDOrn-Gly-aDThr-Thr-Gln-Gly-DSer-cOHOrn

P. fluorescens

CHA0

Q-Asp-FoOHDOrn-Lys-c(Thr-Ala-Ala-FoOHDOrn-Lys)

P. putida bv. B

9BW

Q-DSer-Lys-OHHis-aDThr-Ser-cOHOrn

P. putida

CFBP 2461

Q-Asp-Lys-OHDAsp-Ser-aDThr-Ala-Thr-DLys-cOHOrn

P. tolaasii

NCPPB 2192

Q-DSer-Lys-Ser-DSer-Thr-Ser-AcOHOrn-Thr-DSer-cOHDOrn