What is "pycnodysostosis"

n. (context medicine English) A genetic disorder characterized by dense, fragile bones and dwarfism

n. a form of dwarfism accompanied by fragile bones and bad teeth

Pycnodysostosis (from Greek: πυκνός (puknos) meaning "dense", dys ("defective"), and ostosis ("condition of the bone")), is a lysosomal storage disease of the bone caused by a mutation in the gene that codes the enzyme cathepsin K.