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PWB may refer to:

  • Partial Weight-bearing, in which patients are instructed to put only a certain amount of weight on their leg after surgery
  • Printed wiring board
  • Psychological well-being
  • Programmer's Workbench,
    • an early UNIX from Bell Labs, see PWB/UNIX
    • a Text-based user interface, Integrated development environment (IDE) by Microsoft, see History of Visual C++